Neurological Response to Stress, why:

The neurological response to stress refers to how the brain and nervous system react when you perceive a threat, challenge, or pressure — basically when you’re under stress. This reaction is automatic and deeply wired into us for survival.

(Consult a Medical Doctor if you have any Medical questions.)

Here’s how it works in simple terms:

1. Perception of Stress (Triggering the Response)
It all starts in the amygdala, a part of your brain involved in processing emotions like fear and anxiety.

When the amygdala detects a potential threat, it sends a distress signal to the hypothalamus, the brain’s command center for managing stress responses.

2. Fight-or-Flight Activation (Sympathetic Nervous System)
The hypothalamus activates the sympathetic nervous system.

This triggers the adrenal glands (on top of your kidneys) to release adrenaline (epinephrine).

Effects of adrenaline:

Increased heart rate

Faster breathing

Pupil dilation

Energy boost (glucose released into bloodstream)

Heightened alertness

This is your classic “fight-or-flight” mode.

3. Sustained Stress Response (HPA Axis)
If the stress continues, your brain activates the HPA axis (Hypothalamus–Pituitary–Adrenal axis).

This leads to the release of cortisol, the primary stress hormone.

Cortisol helps keep you alert and gives your body more energy — but long-term, high levels can be damaging.

4. Return to Balance (Parasympathetic Nervous System)
Once the threat passes, the parasympathetic nervous system (the “rest and digest” system) kicks in to calm you down.

Heart rate slows, cortisol levels drop, and the body goes back to normal.

When Stress Becomes Chronic
If this system is constantly activated (due to chronic stress), it can lead to problems like:

Anxiety and depression

Memory issues (especially in the hippocampus, which is sensitive to cortisol)

Weakened immune system

Digestive problems

Heart disease

(Consult a Medical Doctor if you have any Medical questions.)

Shervan K Shahhian